MHMD-4.2 Reduce the proportion of adults aged 18 years and older who experience major depressive episodes (MDEs)

National Data Source
National Survey on Drug Use and Health (NSDUH); Substance Abuse and Mental Health Services Administration (SAMHSA)
Changed Since the Healthy People 2020 Launch
Baseline (Year)
6.4 (2008)
Target-Setting Method
10 percent improvement
Number of adults aged 18 or older with Major Depressive Episode (MDE)
Number of adults aged 18 or older
Data Collection Frequency
Comparable Healthy People 2010 Objective
Not applicable


Methodology Notes

The MDE statistics are annual (last twelve month) prevalence rates.

A modified version of the Composite International Diagnostic Interview is administered to assess criteria necessary for a diagnosis of Major Depressive Episode based on DSM IV for adults. A person was defined as having had a depressive episode (MDE) if he or she had a period of time in the past 12 months when he or she felt depressed or lost interest or pleasure in daily activities for 2 weeks or longer, and had at least five or more of the following nine symptoms in the same 2-week period, in which at least one of the symptoms was a depressed mood or loss of interest or pleasure in daily activities: (1) depressed mood most of the day, nearly every day; (2) markedly diminished interest or pleasure in all or almost all activities most of the day, nearly every day; (3) significant weight loss when not dieting or weight gain or decrease or increase in appetite nearly every day; (4) insomnia or hypersomnia nearly every day; (5) psychomotor agitation or retardation nearly every day; (6) fatigue or loss of energy nearly every day; (7) feelings of worthlessness nearly every day; (8) diminished ability to think or concentrate or indecisiveness nearly every day; and (9) recurrent thoughts of death or recurrent suicide ideation.

Description of Changes Since the Healthy People 2020 Launch

The original baseline was revised from 6.8 to 6.4 due to a change in programming. The target was adjusted from 6.1 to 5.8 to reflect the revised baseline using the original target-setting method.